Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery (R01 Basic Experimental Studies with Humans Required)

Program Description

NIMHD supports research projects that seek to explain the underlying mechanisms, processes, and trajectories of social relationships and how these factors affect outcomes in human health, illness, recovery, and overall wellbeing. Projects submitted through NIMHD must include a focus on one or more NIH-designated populations experiencing health disparities in the United States, which include Blacks/African Americans, Hispanics/Latinos, American Indians/Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, socioeconomically disadvantaged populations, underserved rural populations, and sexual and gender minorities.

The trans-NIH Basic Behavioral and Social Science Opportunity Network (OPPNET), which leads this funding opportunity announcement (FOA), supports research activities that build the collective body of knowledge on the nature of behaviors and social systems and deepen our understanding of basic social-behavioral mechanisms and processes. It is well-established that social ties can facilitate overall wellbeing, recovery from acute illness, and self-management of chronic conditions. Less well understood are the processes by which connection and isolation lead to positive or negative impacts on health, wellbeing, illness, or recovery.

As a participating organization in this funding opportunity announcement, NIMHD seeks to understand the interrelation between social connectedness and social isolation and minority health and health disparities. Topics may include:

  • Impact of social connectedness and social isolation on populations experiencing health disparities and health disparities.
  • Positive and negative impacts of social connectedness and social isolation.
  • Unique challenges for populations experiencing health disparities.
  • Identification of intervention targets for populations experiencing health disparities.
  • Impact of interpersonal and systemic discrimination and microaggressions on social connectedness and social isolation.
  • Impact of neighborhood/place, poverty, stigma, on social connectedness and social isolation.
  • Impact of diverse cultures on social connectedness and social isolation.

Applications proposing observational studies involving humans should submit under the companion FOA PAR-21-145 “Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery (R01 Clinical Trials Not Allowed).”

NIH Guide No.: PAR-21-144 (Reissue of PAR-19-384)


Page updated Jan. 12, 2024